SCHEMBL628485

SCHEMBL628485

Cc1cccc(-c2ccc(N)cc2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.62
HSD17B10 Q99714 2/20 0.62
RAB9A P51151 2/20 0.62
TP53 P04637 2/20 0.62
NPC1 O15118 1/20 0.62
POLB P06746 1/20 0.62
HPGD P15428 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
TAAR1 Q96RJ0 2/20 0.57
ACHE P22303 2/20 0.55
CYP3A4 P08684 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
MAP4K4 O95819 1/20 0.50
ENPP3 O14638 1/20 0.49
MAOA P21397 1/20 0.48
MAPK14 Q16539 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
FNTA P49354 1/20 0.46
FNTB P49356 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30537941 1.00 ALDH1A1 (0.62) ALDH1A1HSD17B10RAB9ATP53NPC1
SCHEMBL16519834 0.98 ALDH1A1 (0.61) ALDH1A1HSD17B10RAB9ATP53NPC1
SCHEMBL19901315 0.89 MAOA (0.64) ALDH1A1HSD17B10RAB9ATP53NPC1
Aniline SCHEMBL27686013 0.89 MAOA (0.64) ALDH1A1HSD17B10RAB9ATP53NPC1
SCHEMBL6561397 0.88 ACHE (0.61) ALDH1A1HSD17B10RAB9ATP53NPC1
SCHEMBL3867124 0.87 RAB9A (0.51) ALDH1A1HSD17B10RAB9ATP53NPC1
SCHEMBL13448183 0.87 MAOA (0.61) ALDH1A1HSD17B10RAB9ATP53NPC1
SCHEMBL18960511 0.86 ACHE (0.59) ALDH1A1HSD17B10RAB9ATP53NPC1
SCHEMBL19446613 0.86 ACHE (0.59) ALDH1A1HSD17B10RAB9ATP53NPC1
SCHEMBL11397076 0.86 ALDH1A1 (0.50) ALDH1A1HSD17B10RAB9ATP53NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1919875-A2 PYRAZOLE DERIVATIVES AND THEIR USE AS PKA AND PKB MODULATORS Astex Therapeutics Limited (GB) 2008-05-14 EP claimed
WO-2006136829-A2 PYRAZOLE DERIVATIVES AND THEIR USE AS PKA AND PKB MODULATORS ASTEX THERAPEUTICS LIMITED (GB) 2006-12-28 WO claimed
EP-4395499-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2024-07-03 EP disclosed
EP-4306612-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2024-01-17 EP disclosed
EP-4273206-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2023-11-08 EP disclosed
EP-3722301-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2023-11-01 EP disclosed
EP-3725793-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2023-10-11 EP disclosed
US-20230320190-A1 ORGANIC LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-05 US disclosed
US-20230303537-A1 NITROGEN-CONTAINING COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-09-28 US disclosed
CN-116635388-A Heterocyclic compound, organic light-emitting element comprising same, method for producing same, and composition for organic layer of organic light-emitting element LT素材株式会社 2023-08-22 CN disclosed
EP-4203661-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2023-06-28 EP disclosed
US-5705686-A 3-MERCAPTO-2-AMINO-PROPYLAMINOBIPHENYL DERIVATIVES; PEPTIDOMIMETICS; ANTICARCINOGENIC AGENTS UNIVERSITY OF PITTSBURGH (US) 1998-01-06 US disclosed
EP-0794789-A1 INHIBITORS OF PRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 1997-09-17 EP disclosed
WO-1997017070-A1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 1997-05-15 WO disclosed
WO-1996021456-A1 INHIBITORS OF PRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 1996-07-18 WO disclosed
US-5480871-A TREATMENT OF BENIGN PROSTATIC HYPERPLASIA CHIRON CORPORATION (US) 1996-01-02 US disclosed
US-5447916-A Hypotensive agents CHIRON CORPORATION (US) 1995-09-05 US disclosed
WO-1995004072-A1 PEPTOID ALPHA-1 ADRENERGIC RECEPTOR LIGANDS CHIRON CORPORATION (US) 1995-02-09 WO disclosed
EP-0139444-A1 Continuous process for the synthesis of unsymmetrical, substituted diphenylamines XEROX CORPORATION (US) 1985-05-02 EP disclosed
US-4485260-A Preparation of unsymmetrical diphenylamines XEROX CORPORATION (US) 1984-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303537-A1 NITROGEN-CONTAINING COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF NPM1, NFE2L2, MNS1 ALDH1A1 2635/4885HSD17B10 4711/4885RAB9A 1916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.