Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27667113 | 0.82 | IKBKB (0.50) | CHRNA7EGLN1GRIN2BPDGFRBPDGFRA | |
| SCHEMBL5547230 | 0.81 | MAPT (0.41) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23484278 | 0.78 | CHRNA7 (0.49) | CHRNA7EGLN1GRIN2BPDGFRBPDGFRA | |
| SCHEMBL27686103 | 0.78 | ERN1 (0.44) | EGLN1GRIN2BPDGFRBPDGFRASLC6A4 | |
| SCHEMBL27686153 | 0.77 | CHRNA7 (0.47) | CHRNA7EGLN1GRIN2BPDGFRBPDGFRA | |
| SCHEMBL16634586 | 0.75 | SLC6A4 (0.51) | EGLN1SLC6A4SLC6A3NPC1CASP3 | |
| SCHEMBL22116633 | 0.73 | NPSR1 (0.39) | SMN1; SMN2LMNA | |
| SCHEMBL2906199 | 0.71 | CYP11B1 (0.62) | NPC1RAB9AMAP2K4 | |
| SCHEMBL4715889 | 0.70 | MEN1 (0.41) | NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL5004713 | 0.70 | LMNA (0.44) | NPC1CASP3RAB9ASMN1; SMN2SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1976915-A | HIV integrase inhibitors | SMITHKLINE BEECHAM CORP (US) | 2007-06-06 | — | — | CN | disclosed |