Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.30 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27686146 | 0.93 | CNR2 (0.33) | CNR2GRM2 | |
| SCHEMBL27666974 | 0.91 | CNR2 (0.33) | CNR2GRM2P2RX3TNIKCNR1 | |
| SCHEMBL28765661 | 0.90 | GRM2 (0.36) | CNR2GRM2 | |
| SCHEMBL27686112 | 0.87 | CYP1A2 (0.33) | CNR2CNR1 | |
| SCHEMBL27667115 | 0.86 | OPRM1 (0.35) | CNR2 | |
| SCHEMBL27686188 | 0.86 | GRIN1 (0.40) | GRM2 | |
| SCHEMBL27667073 | 0.84 | — | — | |
| SCHEMBL27686115 | 0.84 | DPP4 (0.34) | CNR2GRM2 | |
| SCHEMBL27686353 | 0.84 | GRIN1 (0.38) | GRM2 | |
| SCHEMBL27667153 | 0.83 | TRPC5 (0.38) | CNR2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1976915-A | HIV integrase inhibitors | SMITHKLINE BEECHAM CORP (US) | 2007-06-06 | — | — | CN | disclosed |