Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | GRK5 | P34947 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27685962 | 0.87 | MEN1 (0.37) | MEN1KMT2AGRM2GRIN2BFYN | |
| SCHEMBL27667153 | 0.86 | TRPC5 (0.38) | CNR2GRM2KCNH2TGFBR1TGFBR2 | |
| SCHEMBL27666966 | 0.86 | MEN1 (0.36) | MEN1KMT2AGRM2GRIN2BFYN | |
| SCHEMBL27686289 | 0.86 | LMNA (0.33) | LMNAGRM2GRIN2B | |
| SCHEMBL28765661 | 0.86 | GRM2 (0.36) | MEN1KMT2AALDH1A1HSD17B10CNR2 | |
| SCHEMBL27686159 | 0.84 | CNR2 (0.34) | CNR2GRM2 | |
| SCHEMBL27686188 | 0.84 | GRIN1 (0.40) | ALDH1A1GRM2GRIN2BKDM4ENPSR1 | |
| SCHEMBL27686353 | 0.84 | GRIN1 (0.38) | LMNASMN1; SMN2ALDH1A1GRM2GRIN2B | |
| SCHEMBL27667064 | 0.84 | GRIN2B (0.42) | SMN1; SMN2ALDH1A1GRIN2B | |
| SCHEMBL27667097 | 0.83 | GRIN2B (0.41) | SMN1; SMN2ALDH1A1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1976915-A | HIV integrase inhibitors | SMITHKLINE BEECHAM CORP (US) | 2007-06-06 | — | — | CN | disclosed |