Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP13 | P45452 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4483494 | 0.78 | RORC (0.47) | RORCMEN1KMT2AMMP13 | |
| SCHEMBL27562125 | 0.76 | PARP10 (0.44) | NPC1MAPTRAB9A | |
| SCHEMBL27745927 | 0.76 | — | — | |
| SCHEMBL27992580 | 0.75 | KDM1A (0.40) | TACR1SLC6A4SLC6A3 | |
| SCHEMBL27992795 | 0.75 | RPS6KB1 (0.41) | SLC6A4SLC6A3 | |
| SCHEMBL27988950 | 0.74 | LMNA (0.33) | MAPT | |
| SCHEMBL27487851 | 0.73 | ELANE (0.31) | — | |
| SCHEMBL27657835 | 0.72 | RAB9A (0.42) | NPC1MAPTRAB9A | |
| SCHEMBL3885846 | 0.72 | RAB9A (0.39) | TACR1MMP13NPC1MAPTRAB9A | |
| SCHEMBL27613813 | 0.70 | POLB (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843871-A | Heterocyclic compound | 武田药品工业株式会社 | 2019-06-04 | — | — | CN | disclosed |
| CN-101061095-A | Cycloalkyl piperidine tachykinin receptor antagonists | MERCK & CO INC (US) | 2007-10-24 | — | — | CN | disclosed |