Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27667069 | 0.94 | FEN1 (0.34) | GRM2GRIN2BPLK1GRIN1 | |
| SCHEMBL27686161 | 0.92 | TRPV1 (0.33) | LMNARXFP1GRM2NPC1CYP3A4 | |
| SCHEMBL6061367 | 0.90 | GRM2 (0.35) | LMNARXFP1GRM2NPC1CYP3A4 | |
| SCHEMBL27686115 | 0.86 | DPP4 (0.34) | LMNAGRM2GRIN2B | |
| SCHEMBL27667153 | 0.85 | TRPC5 (0.38) | GRM2PLK1 | |
| SCHEMBL27686081 | 0.84 | LMNA (0.35) | LMNARXFP1GRM2ROCK2GRIN2B | |
| SCHEMBL28765661 | 0.84 | GRM2 (0.36) | GRM2CYP3A4GRIN2BGRIN1 | |
| SCHEMBL27667064 | 0.84 | GRIN2B (0.42) | GRIN2BGRIN1 | |
| SCHEMBL27685962 | 0.83 | MEN1 (0.37) | GRM2GRIN2B | |
| SCHEMBL27667097 | 0.83 | GRIN2B (0.41) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1976915-A | HIV integrase inhibitors | SMITHKLINE BEECHAM CORP (US) | 2007-06-06 | — | — | CN | disclosed |