Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21268144 | 0.91 | CYP1A2 (0.41) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL702267 | 0.85 | HPGD (0.39) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL2956325 | 0.84 | L3MBTL1 (0.38) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL687572 | 0.82 | MAPT (0.39) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL706888 | 0.81 | IDO1 (0.36) | ALDH1A1MEN1KMT2AHTR7SMN1; SMN2 | |
| SCHEMBL8345642 | 0.81 | TDP1 (0.34) | HPGDKDM4EALDH1A1MAPTHTR7 | |
| SCHEMBL16240200 | 0.81 | KDM4E (0.44) | HPGDKDM4ETP53HTR7SMN1; SMN2 | |
| SCHEMBL17046320 | 0.81 | MAPT (0.38) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL16240198 | 0.81 | HTR7 (0.60) | KDM4EALDH1A1HTR7SMN1; SMN2LMNA | |
| SCHEMBL162033 | 0.78 | L3MBTL1 (0.40) | HPGDKDM4EALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102993166-B | Preparation method and application of 3H-1,2-dithiole-3-thioketone compound | UNIV SOOCHOW | 2015-05-13 | — | — | CN | claimed |
| CN-102993166-A | Preparation method and application of 3H-1,2-dithiole-3-thioketone compound | UNIV SOOCHOW | 2013-03-27 | — | — | CN | claimed |
| EP-2900645-B1 | HERBICIDAL AND FUNGICIDAL 3-PHENYLISOXAZOLIN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2019-08-21 | — | — | EP | disclosed |
| US-9585392-B2 | 3-phenylisoxazolin derivatives with herbicidal action | BAYER CROPSCIENCE AG (DE) | 2017-03-07 | — | — | US | disclosed |
| US-20150245615-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | BAYER CROPSCIENCE AG (DE) | 2015-09-03 | — | — | US | disclosed |
| CN-102993166-B | Preparation method and application of 3H-1,2-dithiole-3-thioketone compound | UNIV SOOCHOW | 2015-05-13 | — | — | CN | disclosed |
| CN-102993166-A | Preparation method and application of 3H-1,2-dithiole-3-thioketone compound | UNIV SOOCHOW | 2013-03-27 | — | — | CN | disclosed |
| US-20090163535-A1 | Substituted Heteroarylalkanoic Acids | THE INSTITUES FOR PHARMACEUTICAL DISCOVERY, INC. (US) | 2009-06-25 | — | — | US | disclosed |
| EP-1444228-B1 | SUBSTITUTED HETEROARYLALKANOIC ACIDS AND THEIR USE AS ALDOSE REDUCTASE INHIBITORS | INST FOR PHARM DISCOVERY INC (US) | 2008-05-21 | — | — | EP | disclosed |
| US-7361671-B2 | Substituted heteroarylalkanoic acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY, INC. (US) | 2008-04-22 | — | — | US | disclosed |
| US-20070299117-A1 | Hydroxypropylaimines | PHARMACIA & UPJOHN COMPANY | 2007-12-27 | — | — | US | disclosed |
| US-7244755-B2 | Hydroxypropylamines | PHARMACIA & UPJOHN COMPANY (US) | 2007-07-17 | — | — | US | disclosed |
| EP-1444228-A2 | SUBSTITUTED HETEROARYLALKANOIC ACIDS AND THEIR USE AS ALDOSE REDUCTASE INHIBITORS | The Institutes for Pharmaceutical Discovery, LLC (US) | 2004-08-11 | — | — | EP | disclosed |
| EP-1432674-A2 | HYDROXYPROPYLAMINES | Elan Pharmaceuticals, Inc. (US) | 2004-06-30 | — | — | EP | disclosed |
| US-20030166668-A1 | Substituted heteroarylalkanoic acids | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, INC. A CORPORATION OF THE STATE OF DELAWARE | 2003-09-04 | — | — | US | disclosed |
| US-20030125365-A1 | Hydroxypropylamines | PHARMACIA & UPJOHN COMPANY | 2003-07-03 | — | — | US | disclosed |
| WO-2003044015-A2 | SUBSTITUTED HETEROARYLALKANOIC ACIDS AND THEIR USE AS ALDOSE REDUCTASE INHIBITORS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2003-05-30 | — | — | WO | disclosed |
| WO-2003029169-A2 | HYDROXYPROPYLAMINES | ELAN PHARMACEUTICALS, INC. (US) | 2003-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125365-A1 | Hydroxypropylamines | BACE1, PSEN1, APP | HPGD 528/4885KDM4E 3378/4885ALDH1A1 1278/4885 |
| US-20090163535-A1 | Substituted Heteroarylalkanoic Acids | GPR119, LIPA, LIPC | HPGD 1443/4885KDM4E 4022/4885ALDH1A1 227/4885 |
| US-20070299117-A1 | Hydroxypropylaimines | BACE1, APP, BACE2 | HPGD 187/4885KDM4E 4151/4885ALDH1A1 979/4885 |
| US-20030166668-A1 | Substituted heteroarylalkanoic acids | GPR119, LIPA, DDC | HPGD 1349/4885KDM4E 4051/4885ALDH1A1 270/4885 |
| US-20150245615-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | CYP4X1, CBR3, PAOX | HPGD 1114/4885KDM4E 2719/4885ALDH1A1 1019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.