Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | PNP | P00491 | 2/20 | 0.38 |
| ▸ | PARN | O95453 | 1/20 | 0.38 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21499645 | 0.70 | GDA (0.46) | CYP11B2TSHRGAAPKMGDA | |
| SCHEMBL14618904 | 0.67 | TSHR (0.48) | CYP11B2TSHRGAAPKMGDA | |
| SCHEMBL27686769 | 0.65 | — | — | |
| SCHEMBL22105567 | 0.64 | TSHR (0.45) | CYP11B2TSHRGAAPKMGDA | |
| SCHEMBL16068380 | 0.63 | CYP11B2 (0.54) | CYP11B2TSHRGAAPKMGDA | |
| SCHEMBL11069322 | 0.61 | GAA (0.44) | CYP11B2TSHRGAAPKMALDH1A1 | |
| SCHEMBL4958156 | 0.60 | PKM (0.69) | CYP11B2TSHRGAAPKMTNF | |
| SCHEMBL22751731 | 0.60 | CYP11B2 (1.00) | CYP11B2CYP11B1 | |
| SCHEMBL7816003 | 0.59 | HPGD (0.49) | TSHRGAAPKMALDH1A1PNP | |
| SCHEMBL8179399 | 0.59 | SMN1; SMN2 (0.49) | TSHRGAAPKMALDH1A1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100500664-C | Imidazole [1,2-alpha] purine derivative, method of producing same and use thereof | SHANGHAI INST PHARM INDUSTRY (CN) | 2009-06-17 | — | — | CN | disclosed |
| CN-1966505-A | Imidazole [1,2-alpha] purine derivative, method of producing same and use thereof | SHANGHAI INST PHARM INDUSTRY (CN) | 2007-05-23 | — | — | CN | disclosed |