Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1829639 | 0.70 | TP53 (0.37) | ERN1GABRA1GABRB2 | |
| SCHEMBL28765675 | 0.69 | GRM1 (0.33) | — | |
| SCHEMBL4378835 | 0.68 | GABRA1 (0.58) | ERN1GABRA1GABRB1GABRB2 | |
| SCHEMBL7519487 | 0.67 | KMT2A (0.51) | ERN1GABRA1GABRB1 | |
| SCHEMBL16096105 | 0.66 | ERN1 (0.52) | ERN1TYR | |
| SCHEMBL1831694 | 0.65 | GABRA1 (0.33) | GABRA1GABRB2 | |
| SCHEMBL28855979 | 0.64 | GABRA1 (0.32) | GABRA1GABRB2 | |
| SCHEMBL1827944 | 0.64 | GAA (0.44) | — | |
| SCHEMBL15239771 | 0.64 | TRPA1 (0.43) | ERN1GABRA1GABRB1GABRB2TYR | |
| SCHEMBL933028 | 0.63 | GABRA1 (0.50) | GABRA1GABRB1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101061105-A | Potentiators of glutamate receptors | LILLY CO ELI (US) | 2007-10-24 | — | — | CN | disclosed |