Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | ERN1 | O75460 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20280271 | 0.81 | TP53 (0.42) | KMT2AMEN1MAPTHTTMAPK1 | |
| SCHEMBL5217971 | 0.79 | ERN1 (0.50) | KMT2AMEN1MAPTHTTMAPK1 | |
| SCHEMBL27624284 | 0.79 | PSEN1 (0.41) | KMT2AMEN1MAPTHTTMAPK1 | |
| SCHEMBL27624253 | 0.79 | CYP3A4 (0.41) | KMT2AMEN1MAPTHTTMAPK1 | |
| SCHEMBL815863 | 0.78 | MEN1 (0.59) | KMT2AMEN1MAPTHTTMAPK1 | |
| SCHEMBL51491 | 0.78 | MEN1 (0.59) | KMT2AMEN1MAPTHTTMAPK1 | |
| SCHEMBL27655281 | 0.78 | HTT (0.36) | KMT2AMEN1MAPTHTTMAPK1 | |
| SCHEMBL27506948 | 0.78 | ERN1 (0.48) | KMT2AMEN1MAPTHTTNPSR1 | |
| SCHEMBL27798051 | 0.78 | CA3 (0.38) | HTTALDH1A1GAAALOX12HIF1A | |
| SCHEMBL838659 | 0.77 | TP53 (0.57) | KMT2AMEN1MAPTHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101855224-B | Equilibrative nucleoside transporter ENT1 inhibitors | JANSSEN PHARMACEUTICA NV | 2012-11-28 | — | — | CN | disclosed |
| CN-101855224-A | Equilibrative nucleoside transporter ENT 1 inhibitors | JANSSEN PHARMACEUTICA NV | 2010-10-06 | — | — | CN | disclosed |
| EP-0743311-B1 | FLAVANONOL DERIVATIVES AND HAIR NOURISHMENT AND GROWTH STIMULANT COMPOSITION CONTAINING THE SAME | KAO CORP (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5876703-A | CELL DIFFERENTIATION OF HAIR MATRIX CELLS | KAO CORPORATION (JP) | 1999-03-02 | — | — | US | disclosed |
| US-5702691-A | Flavanonol derivatives and hair-nourishing, hair growing compositions containing the derivatives | KAO CORPORATION (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0743311-A1 | FLAVANONOL DERIVATIVES AND HAIR NOURISHMENT AND GROWTH STIMULANT COMPOSITION CONTAINING THE SAME | Kao Corporation (JP) | 1996-11-20 | — | — | EP | disclosed |