Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28765674 | 0.76 | GRM1 (0.37) | GRM1CYP3A4TSHRPIK3CA | |
| SCHEMBL28749906 | 0.74 | CYP3A4 (0.48) | CYP3A4TSHRPIK3CA | |
| SCHEMBL21042111 | 0.70 | TDP1 (0.45) | CYP3A4TSHR | |
| SCHEMBL1801222 | 0.69 | CYP3A4 (0.48) | CYP3A4TSHRPIK3CA | |
| SCHEMBL29283145 | 0.67 | TDP2 (0.31) | — | |
| SCHEMBL15239771 | 0.67 | TRPA1 (0.43) | CYP3A4TSHR | |
| SCHEMBL5201009 | 0.66 | TSHR (0.33) | CYP3A4TSHRPIK3CA | |
| SCHEMBL6538658 | 0.65 | CYP3A4 (0.43) | CYP3A4TSHRPIK3CA | |
| SCHEMBL126200 | 0.65 | ALDH1A1 (0.43) | CYP3A4TSHRPIK3CA | |
| SCHEMBL29631738 | 0.65 | ALDH1A1 (0.43) | CYP3A4TSHRPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101955470-B | Potentiators of glutamate receptors | LILLY CO ELI | 2012-06-13 | — | — | CN | disclosed |
| CN-101955470-A | Glutamate receptor potentiators | LILLY CO ELI | 2011-01-26 | — | — | CN | disclosed |
| CN-101061106-B | Glutamate receptor potentiators | LILLY CO ELI | 2010-09-29 | — | — | CN | disclosed |
| CN-101061106-A | Glutamate receptor potentiators | LILLY CO ELI (US) | 2007-10-24 | — | — | CN | disclosed |