Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28758520 | 0.80 | MTNR1A (0.53) | MTNR1AMTNR1BMAOAMAOBMCL1 | |
| SCHEMBL8801364 | 0.78 | ALDH1A1 (0.52) | MTNR1AMTNR1BMAOAMAOBMCL1 | |
| SCHEMBL6086725 | 0.77 | HDAC8 (0.53) | MTNR1AMTNR1BMAOAMAOBMCL1 | |
| SCHEMBL20072247 | 0.76 | CYP2A6 (0.47) | MTNR1AMTNR1BMAOAMAOBCA12 | |
| SCHEMBL27774875 | 0.76 | MTNR1A (0.55) | MTNR1AMTNR1BMAOAMAOBMCL1 | |
| Fumaric Acid SCHEMBL8001749 | 0.75 | HTR2C (0.51) | MTNR1AMTNR1BMAOAMAOBMCL1 | |
| SCHEMBL27927263 | 0.74 | MCL1 (0.48) | MCL1KDM4EPOLBPPARGPPARD | |
| SCHEMBL14036317 | 0.73 | PPARG (0.77) | MCL1PPARGPPARDPPARA | |
| SCHEMBL27657208 | 0.73 | HDAC8 (0.48) | MTNR1AMTNR1BMAOAMAOBHTR2A | |
| SCHEMBL27730706 | 0.72 | KDM4E (0.47) | MTNR1AMTNR1BMAOAMAOBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101048391-A | Tetracyclic indole derivatives as antiviral agents | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-10-03 | — | — | CN | disclosed |