Malonic Acid

Malonic Acid

SCHEMBL27693136

CCC[N+](C)(C)C.O=C(O)CC(=O)O

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.47
SRR Q9GZT4 1/20 0.47
TSHR P16473 1/20 0.43
LMNA P02545 2/20 0.42
APEX1 P27695 2/20 0.42
ALDH1A1 P00352 1/20 0.42
FFAR3 O14843 2/20 0.39
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
ACHE P22303 1/20 0.37
CHRM2 P08172 2/20 0.37
CHRM4 P08173 2/20 0.37
CHRM5 P08912 2/20 0.37
CHRM1 P11229 2/20 0.37
CHRNB2 P17787 2/20 0.37
CHRM3 P20309 2/20 0.37
CHRNA7 P36544 2/20 0.37
CHRNA4 P43681 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL29127597 0.86 TSHR (0.43) TSHRLMNAAPEX1ALDH1A1FFAR3
Malonic Acid SCHEMBL8437818 0.81 DNM1 (0.65) TSHRALDH1A1DNM1
Cetrimonium SCHEMBL8434405 0.81 DNM1 (0.65) TSHRALDH1A1DNM1
Malonic Acid SCHEMBL8436856 0.81 DNM1 (0.65) TSHRALDH1A1DNM1
Bicarbonate SCHEMBL9499506 0.81 BBOX1 (0.42) TSHRLMNAAPEX1ALDH1A1FFAR3
Tetrapropylammonium SCHEMBL104364 0.81 SLC22A1 (0.56) LDHASRRTSHRALDH1A1FFAR3
Malonic Acid SCHEMBL27693147 0.80 LDHA (0.56) LDHASRRTSHRLMNAAPEX1
Ammonia Solution, Strong SCHEMBL28799262 0.80 CHRM5 (0.39) TSHRLMNAAPEX1ACHECHRM2
Choline SCHEMBL21380519 0.79 LMNA (0.60) LDHASRRTSHRLMNAAPEX1
Valeric Acid SCHEMBL5574483 0.78 AKR1B1 (0.58) TSHRLMNAAPEX1ALDH1A1FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101104149-A Stabilized carbanions as trimerization catalysts AIR PROD & CHEM (US) 2008-01-16 CN claimed
CN-101104149-B Stabilized carbanions as trimerization catalysts AIR PROD & CHEM 2012-03-28 CN disclosed
CN-101104149-A Stabilized carbanions as trimerization catalysts AIR PROD & CHEM (US) 2008-01-16 CN disclosed