Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 8/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 8/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 2/20 | 0.36 |
| ▸ | FNTB | P49356 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17339104 | 0.79 | KDM4E (0.52) | ALDH1A1KDM4EHPGDKMT2AGLA | |
| SCHEMBL17339134 | 0.79 | FNTA (0.48) | ALDH1A1KDM4EHPGDKMT2ATSHR | |
| SCHEMBL27696643 | 0.77 | BAZ2B (0.40) | ALDH1A1KDM4EHPGDBAZ2BBAZ2A | |
| SCHEMBL5259049 | 0.75 | FNTA (0.62) | KMT2ABAZ2BBAZ2ABRD4BRD2 | |
| SCHEMBL27795128 | 0.73 | EGFR (0.46) | ALDH1A1KDM4EHPGDKMT2ATSHR | |
| SCHEMBL7441083 | 0.71 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDKMT2ATSHR | |
| SCHEMBL1778700 | 0.69 | KDM4E (0.49) | ALDH1A1KDM4EHPGDKMT2ATSHR | |
| SCHEMBL21202651 | 0.69 | RAB9A (0.50) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL20229736 | 0.66 | NPC1 (0.53) | ALDH1A1KDM4EHPGDKMT2ATSHR | |
| SCHEMBL27746851 | 0.66 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101094852-A | Substituted indolizines and derivatives as CNS active agents | WYETH CORP (US) | 2007-12-26 | — | — | CN | disclosed |