Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 4/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 6/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17339134 | 0.81 | FNTA (0.48) | LMNATSHRBAZ2BBAZ2AKDM4E | |
| SCHEMBL5259049 | 0.77 | FNTA (0.62) | BAZ2BBAZ2AFNTAFNTBHTT | |
| SCHEMBL27696466 | 0.73 | ALDH1A1 (0.40) | TSHRBAZ2BBAZ2AKDM4EALDH1A1 | |
| SCHEMBL17339104 | 0.73 | KDM4E (0.52) | SMN1; SMN2ELANEKDM4EALDH1A1GAA | |
| SCHEMBL27746851 | 0.67 | ALDH1A1 (0.41) | LMNATSHRSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1778700 | 0.67 | KDM4E (0.49) | LMNATSHRKDM4EALDH1A1GAA | |
| SCHEMBL543429 | 0.66 | RORC (0.40) | — | |
| SCHEMBL27767828 | 0.65 | MAOA (0.46) | LMNASMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL10123875 | 0.64 | RORC (0.48) | — | |
| SCHEMBL7441083 | 0.64 | ALDH1A1 (0.42) | LMNATSHRSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101659663-B | Indolizine derivative as well as preparation method and application thereof | UNIV SHAOXING | 2011-06-08 | — | — | CN | disclosed |
| CN-101659663-A | Indolizine derivative as well as preparation method and application thereof | UNIV SHAOXING | 2010-03-03 | — | — | CN | disclosed |