Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 11/20 | 0.40 |
| ▸ | BAZ2A | Q9UIF9 | 11/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.37 |
| ▸ | ICMT | O60725 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27696466 | 0.77 | ALDH1A1 (0.40) | BAZ2BBAZ2ABRD4BRD9BRD2 | |
| SCHEMBL29882866 | 0.70 | FNTA (0.48) | BAZ2BBAZ2ABRD4BRD9BRD2 | |
| SCHEMBL17339103 | 0.69 | BAZ2B (0.49) | BAZ2BBAZ2ABRD4BRD9BRD2 | |
| SCHEMBL21202651 | 0.67 | RAB9A (0.50) | POLBKDM4EMAPTTP53ALDH1A1 | |
| SCHEMBL4268676 | 0.63 | ICMT (0.42) | ICMTPOLBKDM4ELMNAMAPK1 | |
| SCHEMBL3261349 | 0.63 | ICMT (0.40) | ICMTPOLBKDM4ELMNAMAPK1 | |
| SCHEMBL29882630 | 0.62 | FNTA (0.48) | BAZ2BBAZ2ABRD4BRD9KDM4E | |
| SCHEMBL20229736 | 0.61 | NPC1 (0.53) | KDM4ELMNAMAPTTP53ALDH1A1 | |
| SCHEMBL20346870 | 0.61 | PKM (0.47) | KDM4ETP53ALDH1A1HPGD | |
| SCHEMBL2590889 | 0.61 | GABRA1 (0.44) | ICMTPOLBKDM4ELMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101094852-A | Substituted indolizines and derivatives as CNS active agents | WYETH CORP (US) | 2007-12-26 | — | — | CN | disclosed |