Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27729418 | 0.82 | LMNA (0.52) | ALDH1A1TDP1LMNAGAASMN1; SMN2 | |
| SCHEMBL27751837 | 0.68 | CYP19A1 (0.41) | THRBALDH1A1TDP1LMNAGAA | |
| SCHEMBL25021463 | 0.68 | ANPEP (0.44) | TSHR | |
| Hydrochloric Acid SCHEMBL27533449 | 0.68 | HDAC4 (0.43) | LMNAMEN1KMT2A | |
| SCHEMBL22474196 | 0.67 | PPARG (0.50) | MEN1KMT2APOLB | |
| SCHEMBL21850401 | 0.67 | SLC1A1 (0.45) | LMNAMEN1KMT2A | |
| SCHEMBL13131368 | 0.67 | ALDH1A1 (0.66) | ALDH1A1TDP1LMNAGAASMN1; SMN2 | |
| SCHEMBL27919840 | 0.67 | CYP19A1 (0.46) | THRBALDH1A1CYP19A1ICMT | |
| SCHEMBL27458167 | 0.67 | ALDH1A1 (0.58) | ALDH1A1LMNASMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL9737535 | 0.66 | MAPT (0.57) | TDP1PTGDR2MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101010297-B | N- (1H-indolyl) -1H-indole-2-carboxamide derivatives, their preparation and their pharmaceutical use | SANOFI AVENTIS | 2011-07-27 | — | — | CN | disclosed |
| CN-101010297-A | N- (1H-indolyl) -1H-indole-2-carboxamide derivatives, their preparation and their pharmaceutical use | SANOFI AVENTIS (FR) | 2007-08-01 | — | — | CN | disclosed |