Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824359 | 0.83 | LTA4H (0.44) | SMN1; SMN2DRD3L3MBTL1 | |
| SCHEMBL9053497 | 0.81 | MAPT (0.39) | MAPTRECQLPTGESALOX5PPARG | |
| SCHEMBL27466473 | 0.80 | CHRNB2 (0.40) | SLC2A1SMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL9069754 | 0.79 | MAPT (0.39) | MAPTRECQLSLC2A1HRH3MAPK1 | |
| SCHEMBL8955954 | 0.78 | LTA4H (0.44) | MAPK1SMN1; SMN2 | |
| SCHEMBL9070331 | 0.78 | MAPT (0.38) | MAPTRECQLPTGESALOX5PPARG | |
| SCHEMBL29274538 | 0.76 | NPC1 (0.44) | SMN1; SMN2 | |
| SCHEMBL28903646 | 0.76 | NPC1 (0.44) | SMN1; SMN2 | |
| SCHEMBL4851262 | 0.76 | NPC1 (0.44) | SMN1; SMN2 | |
| SCHEMBL14791134 | 0.74 | DNM1 (0.40) | MAPTRECQLSLC2A1HRH3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101111267-B | Stabilized polymeric thiol reagents | NEKTAR THERAPEUTICS AL CORP | 2012-12-05 | — | — | CN | disclosed |
| CN-101111267-A | Stabilized polymeric thiol reagents | NEKTAR THERAPEUTICS AL CORP (US) | 2008-01-23 | — | — | CN | disclosed |