Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.50 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 5/20 | 0.46 |
| ▸ | RXRB | P28702 | 5/20 | 0.46 |
| ▸ | RXRG | P48443 | 5/20 | 0.46 |
| ▸ | THRA | P10827 | 3/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27697437 | 0.87 | THRB (0.53) | THRBFFAR1RXRARXRBRXRG | |
| SCHEMBL4597814 | 0.82 | PSEN1 (0.58) | THRBFFAR1PSEN1PSEN2APH1B | |
| SCHEMBL27697439 | 0.81 | THRB (0.51) | THRBFFAR1PSEN1PSEN2APH1B | |
| SCHEMBL27697446 | 0.79 | THRB (0.49) | THRBFFAR1PSEN1PSEN2APH1B | |
| SCHEMBL8329343 | 0.78 | LTA4H (0.60) | THRBFFAR1PSEN1PSEN2APH1B | |
| SCHEMBL2984377 | 0.77 | NR1H4 (0.45) | PPARD | |
| SCHEMBL11080030 | 0.76 | GAA (0.64) | THRBSMN1; SMN2NR3C1GAA | |
| SCHEMBL12618448 | 0.74 | HTR2A (0.50) | FFAR1PPARD | |
| SCHEMBL5018905 | 0.73 | L3MBTL1 (0.64) | FFAR1 | |
| SCHEMBL4509606 | 0.72 | MAPT (0.50) | THRBFFAR1SMN1; SMN2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101142185-A | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2008-03-12 | — | — | CN | disclosed |