Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.57 |
| ▸ | RXRA | P19793 | 5/20 | 0.57 |
| ▸ | RXRB | P28702 | 5/20 | 0.57 |
| ▸ | RXRG | P48443 | 5/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.57 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.56 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.56 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.56 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.56 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.56 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL267205 | 0.89 | RXRA (0.68) | RXRARXRBRXRGSRD5A2PSEN1 | |
| Water SCHEMBL28015733 | 0.87 | RXRA (0.66) | RXRARXRBRXRGSRD5A2PSEN1 | |
| Hydrochloric Acid SCHEMBL2528774 | 0.87 | RXRA (0.66) | RXRARXRBRXRGSRD5A2PSEN1 | |
| SCHEMBL3498978 | 0.85 | MAOB (0.67) | RXRARXRBRXRGPPARDPPARA | |
| SCHEMBL21243832 | 0.85 | SRD5A2 (0.72) | SRD5A2THRBTHRAFFAR1NR3C1 | |
| SCHEMBL2999416 | 0.85 | SRD5A2 (0.72) | SRD5A2THRBTHRAFFAR1NR3C1 | |
| SCHEMBL9155110 | 0.85 | LTA4H (0.56) | LTA4HEPHX2MAPK14MEN1KMT2A | |
| SCHEMBL9266226 | 0.85 | LTA4H (0.56) | LTA4HEPHX2SMN1; SMN2MAPK14MEN1 | |
| SCHEMBL11077637 | 0.85 | THRB (0.60) | LTA4HEPHX2SMN1; SMN2MAPK14RXRA | |
| SCHEMBL2272003 | 0.84 | RXRA (0.77) | RXRARXRBRXRGPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4485114-A | Arylglyoxals useful as hypoglycemic agents | AMERICAN CYANAMID COMPANY (US) | 1984-11-27 | — | — | US | claimed |
| EP-0556381-B1 | N-(4-PYRIDYL OR 4-QUINOLINYL) ARYLACETAMIDE PESTICIDES | DOW AGROSCIENCES LLC (US) | 1999-04-28 | — | — | EP | disclosed |
| US-5597836-A | NEMATOCIDES, INSECTICIDES, MITICIDES AND PLANT PATHOGENS | DOWELANCO (US) | 1997-01-28 | — | — | US | disclosed |
| EP-0555469-A4 | 4-(ARALKOXY OR ARALKYLAMINO)PYRIDINE PESTICIDES----------------- | DOWELANCO (US) | 1995-06-21 | — | — | EP | disclosed |
| EP-0556381-A4 | — | DOWELANCO (US) | 1995-06-21 | — | — | EP | disclosed |
| US-5399564-A | N-(4-pyridyl or 4-quinolinyl) arylacetamide and 4-(aralkoxy or aralkylamino) pyridine pesticides | DOWELANCO (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0556381-A1 | N-(4-PYRIDYL OR 4-QUINOLINYL) ARYLACETAMIDE PESTICIDES | DOWELANCO (US) | 1993-08-25 | — | — | EP | disclosed |
| EP-0555469-A1 | 4-(ARALKOXY OR ARALKYLAMINO)PYRIDINE PESTICIDES----------------- | DOWELANCO (US) | 1993-08-18 | — | — | EP | disclosed |
| WO-1993005050-A1 | 4-(ARALKOXY OR ARALKYLAMINO)PYRIDINE PESTICIDES_________________ | DOWELANCO (US) | 1993-03-18 | — | — | WO | disclosed |
| WO-1993004580-A1 | N-(4-PYRIDYL OR 4-QUINOLINYL) ARYLACETAMIDE PESTICIDES | DOWELANCO (US) | 1993-03-18 | — | — | WO | disclosed |
| US-4485114-A | Arylglyoxals useful as hypoglycemic agents | AMERICAN CYANAMID COMPANY (US) | 1984-11-27 | — | — | US | disclosed |