Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28635736 | 0.87 | TSHR (0.47) | TSHRLMNAHSD17B10ALDH1A1CA12 | |
| SCHEMBL27948846 | 0.86 | TSHR (0.47) | TSHRLMNAHSD17B10ALDH1A1CA12 | |
| SCHEMBL9808496 | 0.85 | TSHR (0.46) | TSHRLMNAHSD17B10ALDH1A1CA12 | |
| SCHEMBL787248 | 0.84 | TSHR (0.44) | TSHRLMNAHSD17B10ALDH1A1CA12 | |
| SCHEMBL27584031 | 0.84 | CA1 (0.43) | TSHRLMNAHSD17B10ALDH1A1CA12 | |
| SCHEMBL5872395 | 0.83 | LMNA (0.45) | TSHRLMNAHSD17B10ALDH1A1CA12 | |
| SCHEMBL28023655 | 0.82 | TSHR (0.50) | TSHRLMNAHSD17B10ALDH1A1CA12 | |
| SCHEMBL11381264 | 0.82 | TSHR (0.40) | TSHRLMNAHSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL27562386 | 0.81 | MAOB (0.54) | LMNACA12CA1CA2CA9 | |
| SCHEMBL27593311 | 0.80 | TSHR (0.49) | TSHRLMNAHSD17B10ALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101649203-B | Stabilization of organic materials | CIBA SC HOLDING AG | 2013-12-18 | — | — | CN | disclosed |
| CN-102149736-A | Catalyst for polymerizing olefins and process thereof | BASELL POLIOLEFINE SRL | 2011-08-10 | — | — | CN | disclosed |
| CN-101649203-A | Stabilization of organic materials | CIBA SC HOLDING AG CH | 2010-02-17 | — | — | CN | disclosed |
| CN-101023128-A | Stabilization of organic materials | CIBA SC HOLDING AG (CH) | 2007-08-22 | — | — | CN | disclosed |