Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27698103 | 0.87 | TSHR (0.56) | TSHRLMNAHSD17B10CA12CA1 | |
| SCHEMBL9808496 | 0.87 | TSHR (0.46) | TSHRLMNAHSD17B10CA12CA1 | |
| SCHEMBL787248 | 0.85 | TSHR (0.44) | TSHRLMNAHSD17B10CA12CA1 | |
| SCHEMBL28023655 | 0.84 | TSHR (0.50) | TSHRLMNAHSD17B10CA12CA1 | |
| SCHEMBL27948846 | 0.84 | TSHR (0.47) | TSHRLMNAHSD17B10PSIP1CA12 | |
| SCHEMBL3182768 | 0.81 | LMNA (0.42) | TSHRLMNAHSD17B10CA12CA1 | |
| SCHEMBL5872395 | 0.81 | LMNA (0.45) | TSHRLMNAHSD17B10CA12CA1 | |
| SCHEMBL4751896 | 0.80 | CHRM2 (0.48) | TSHRLMNAHSD17B10ALDH1A1KDM4E | |
| SCHEMBL27671277 | 0.79 | ATM (0.44) | TSHRLMNAHSD17B10CA12CA1 | |
| SCHEMBL9045030 | 0.77 | LMNA (0.48) | TSHRLMNAHSD17B10CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113444086-A | Ezh2 inhibitor and application thereof | 达纳-法伯癌症研究所股份有限公司 | 2021-09-28 | — | — | CN | disclosed |