Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28635736 | 0.85 | TSHR (0.47) | TSHRLMNAHSD17B10CA12CA1 | |
| SCHEMBL528908 | 0.84 | ALDH1A1 (0.46) | LMNACA12CA1CA2CA9 | |
| SCHEMBL9808496 | 0.84 | TSHR (0.46) | TSHRLMNAHSD17B10CA12CA1 | |
| SCHEMBL27698103 | 0.84 | TSHR (0.56) | TSHRLMNAHSD17B10CA12CA1 | |
| SCHEMBL8664446 | 0.83 | F2 (0.44) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL8662610 | 0.83 | NPC1 (0.45) | LMNACA12CA1CA2CA9 | |
| SCHEMBL28478501 | 0.81 | LARS1 (0.49) | TSHRLMNAHSD17B10CA12CA1 | |
| SCHEMBL27948846 | 0.81 | TSHR (0.47) | TSHRLMNAHSD17B10CA12CA1 | |
| SCHEMBL28023655 | 0.81 | TSHR (0.50) | TSHRLMNAHSD17B10CA12CA1 | |
| SCHEMBL28721407 | 0.79 | ATM (0.43) | TSHRLMNAHSD17B10CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8568960-B2 | Multiple exposure photolithography methods | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-10-29 | — | — | US | claimed |
| US-20120178027-A1 | MULTIPLE EXPOSURE PHOTOLITHOGRAPHY METHODS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-07-12 | — | — | US | claimed |
| EP-2240828-A1 | MULTIPLE EXPOSURE PHOTOLITHOGRAPHY METHODS AND PHOTORESIST COMPOSITIONS | International Business Machines Corporation (US) | 2010-10-20 | — | — | EP | claimed |
| WO-2009087029-A1 | MULTIPLE EXPOSURE PHOTOLITHOGRAPHY METHODS AND PHOTORESIST COMPOSITIONS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2009-07-16 | — | — | WO | claimed |
| US-20090176174-A1 | MULTIPLE EXPOSURE PHOTOLITHOGRAPHY METHODS AND PHOTORESIST COMPOSTIONS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2009-07-09 | — | — | US | claimed |
| US-9235119-B2 | Exposure photolithography methods | GLOBALFOUNDRIES INC. (KY) | 2016-01-12 | — | — | US | disclosed |
| US-20140349237-A1 | EXPOSURE PHOTOLITHOGRAPHY METHODS | GLOBALFOUNDRIES U.S. INC. | 2014-11-27 | — | — | US | disclosed |
| US-8846296-B2 | Photoresist compositions | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-09-30 | — | — | US | disclosed |
| CN-103492376-A | Bicyclic heterocycle compounds and their uses in therapy | ASTEX THERAPEUTICS LTD | 2014-01-01 | — | — | CN | disclosed |
| US-8568960-B2 | Multiple exposure photolithography methods | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-10-29 | — | — | US | disclosed |
| US-8394573-B2 | Photoresist compositions and methods for shrinking a photoresist critical dimension | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-03-12 | — | — | US | disclosed |
| US-20120214099-A1 | PHOTORESIST COMPOSITIONS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-08-23 | — | — | US | disclosed |
| WO-2000071513-A1 | CINNAMOYLAMINOALKYL-SUBSTITUTED BENZENESULFONAMIDE DERIVATIVES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-11-30 | — | — | WO | disclosed |
| US-5527805-A | DNA-CLEAVING, CYTOTOXIC AND ANTI-TUMOR COMPOUNDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1996-06-18 | — | — | US | disclosed |
| EP-0594624-A1 | DYNEMICIN ANALOGS: SYNTHESES, METHODS OF PREPARATION AND USE | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1994-05-04 | — | — | EP | disclosed |
| EP-0594624-A4 | DYNEMICIN ANALOGS: SYNTHESES, METHODS OF PREPARATION AND USE. | SCRIPPS CLINIC RES (US) | 1994-02-21 | — | — | EP | disclosed |
| US-5281710-A | Antibiotics or antitumor agents | THE SCRIPPS RESEARCH INSTITUTE (US) | 1994-01-25 | — | — | US | disclosed |
| US-5276159-A | Antitumor | THE SCRIPPS RESEARCH INSTITUTE (US) | 1994-01-04 | — | — | US | disclosed |
| WO-1992002522-A1 | DYNEMICIN ANALOGS: SYNTHESES, METHODS OF PREPARATION AND USE | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1992-02-20 | — | — | WO | disclosed |
| US-3932658-A | Composition and method for lower blood sugar containing N-[4-(β-<2-methoxy-5-chloro-benzamido>-ethyl)-benzenesulfonyl]-N'-cyclopentyl-urea | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | disclosed |