Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 3/20 | 0.41 |
| ▸ | MMP7 | P09237 | 3/20 | 0.41 |
| ▸ | MMP12 | P39900 | 3/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27698103 | 0.86 | TSHR (0.56) | TSHRLMNAHSD17B10ATMRAB9A | |
| SCHEMBL28635736 | 0.84 | TSHR (0.47) | TSHRLMNAHSD17B10HSD11B1ATM | |
| SCHEMBL9045030 | 0.83 | LMNA (0.48) | TSHRLMNAHSD17B10HSD11B1ATM | |
| SCHEMBL9808496 | 0.82 | TSHR (0.46) | TSHRLMNAHSD17B10ATMMMP1 | |
| SCHEMBL787248 | 0.81 | TSHR (0.44) | TSHRLMNAHSD17B10ATMMMP1 | |
| SCHEMBL28023655 | 0.79 | TSHR (0.50) | TSHRLMNAHSD17B10HSD11B1RAB9A | |
| SCHEMBL3182768 | 0.77 | LMNA (0.42) | TSHRLMNAHSD17B10ATMRAB9A | |
| SCHEMBL5872395 | 0.77 | LMNA (0.45) | TSHRLMNAHSD17B10ATMRAB9A | |
| SCHEMBL4751896 | 0.76 | CHRM2 (0.48) | TSHRLMNAHSD17B10ALDH1A1KMT2A | |
| SCHEMBL28089748 | 0.75 | HSD11B1 (0.49) | TSHRLMNAHSD17B10HSD11B1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103509135-A | Olefin polymerization catalyst component, preparation method and application thereof | CHINA PETROLEUM & CHEMICAL | 2014-01-15 | — | — | CN | disclosed |