Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 9/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27679086 | 0.90 | HTT (0.44) | HTR6HTTDRD2 | |
| SCHEMBL4617526 | 0.88 | DRD2 (0.43) | SOS1HTR6HTTSCN7ASCN5A | |
| SCHEMBL27679084 | 0.87 | HTR6 (0.42) | HTR6DRD2HTR2A | |
| SCHEMBL27698157 | 0.86 | DRD2 (0.46) | HTR6HTTDRD2HTR2A | |
| SCHEMBL27698148 | 0.83 | EGFR (0.37) | EGFRERBB2LCKKDRTP53 | |
| SCHEMBL4617544 | 0.80 | DRD2 (0.48) | HTR6HTTKCNH2GPR119SCN7A | |
| SCHEMBL4617179 | 0.77 | HTT (0.45) | HTR6HTTDRD2 | |
| SCHEMBL27698149 | 0.76 | MEN1 (0.43) | DRD2 | |
| SCHEMBL4617689 | 0.74 | DRD2 (0.44) | HTR6DRD2 | |
| SCHEMBL4617537 | 0.74 | HTR6 (0.42) | HTR6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101048161-A | Arylthiobenzylpiperidine Derivatives | LUNDBECK & CO AS H (DK) | 2007-10-03 | — | — | CN | disclosed |