Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | DRD4 | P21917 | 5/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.37 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27679092 | 0.91 | OPRM1 (0.37) | MEN1KMT2ADRD4DRD2DRD3 | |
| SCHEMBL27698148 | 0.90 | EGFR (0.37) | MEN1KMT2ADRD4DRD2DRD3 | |
| SCHEMBL4618239 | 0.86 | MEN1 (0.43) | MEN1KMT2ADRD4DRD2DRD3 | |
| SCHEMBL27679086 | 0.85 | HTT (0.44) | MEN1KMT2ADRD4DRD2DRD3 | |
| SCHEMBL4616580 | 0.78 | ALDH1A1 (0.38) | MEN1KMT2ADRD4DRD2DRD3 | |
| SCHEMBL4615973 | 0.77 | DRD2 (0.41) | MEN1KMT2ADRD4DRD2DRD3 | |
| SCHEMBL27698157 | 0.77 | DRD2 (0.46) | MEN1KMT2ADRD2ACHEALDH1A1 | |
| SCHEMBL4615328 | 0.76 | DRD2 (0.46) | MEN1KMT2ADRD4DRD2DRD3 | |
| SCHEMBL27698155 | 0.76 | SOS1 (0.39) | DRD2 | |
| SCHEMBL27679084 | 0.72 | HTR6 (0.42) | DRD2ACHEBCHEBACE1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101048161-A | Arylthiobenzylpiperidine Derivatives | LUNDBECK & CO AS H (DK) | 2007-10-03 | — | — | CN | disclosed |