Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 2/20 | 0.36 |
| ▸ | CLPP | Q16740 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 4/20 | 0.34 |
| ▸ | DRD4 | P21917 | 4/20 | 0.34 |
| ▸ | DRD3 | P35462 | 4/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27698149 | 0.90 | MEN1 (0.43) | MEN1KMT2AATMDRD2DRD4 | |
| SCHEMBL27679092 | 0.88 | OPRM1 (0.37) | MEN1KMT2AATMDRD2DRD4 | |
| SCHEMBL4615973 | 0.88 | DRD2 (0.41) | AXLCLPPMEN1KMT2AATM | |
| SCHEMBL27698155 | 0.83 | SOS1 (0.39) | EGFRERBB2LCKKDRDRD2 | |
| SCHEMBL4615328 | 0.80 | DRD2 (0.46) | MEN1KMT2AATMDRD2DRD4 | |
| SCHEMBL4618239 | 0.77 | MEN1 (0.43) | MEN1KMT2AATMDRD2DRD4 | |
| SCHEMBL27679086 | 0.76 | HTT (0.44) | MEN1KMT2ADRD2DRD4DRD3 | |
| SCHEMBL4616580 | 0.75 | ALDH1A1 (0.38) | MEN1KMT2AATMDRD2DRD4 | |
| SCHEMBL27698157 | 0.72 | DRD2 (0.46) | MEN1KMT2ADRD2ACHE | |
| SCHEMBL27679084 | 0.72 | HTR6 (0.42) | DRD2BCHEACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101048161-A | Arylthiobenzylpiperidine Derivatives | LUNDBECK & CO AS H (DK) | 2007-10-03 | — | — | CN | disclosed |