Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27698323 | 0.93 | EPHX1 (0.46) | PNMTCES2HSD17B2OPRL1OPRM1 | |
| SCHEMBL4157268 | 0.86 | PNMT (0.58) | PNMTCES2HSD17B2OPRL1OPRM1 | |
| SCHEMBL29750658 | 0.79 | HTR2C (0.54) | PNMTCES2HSD17B2OPRL1OPRM1 | |
| SCHEMBL11276420 | 0.76 | PNMT (0.50) | PNMTCES2HSD17B2OPRL1OPRM1 | |
| Hydrochloric Acid SCHEMBL11275846 | 0.75 | PNMT (0.49) | PNMTCES2HSD17B2OPRL1OPRM1 | |
| SCHEMBL8990296 | 0.74 | PNMT (0.46) | PNMTCES2HSD17B2OPRL1OPRM1 | |
| SCHEMBL4135956 | 0.71 | PNMT (0.65) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL11402437 | 0.71 | HIF1A (0.56) | PNMTOPRM1OPRK1EPHX1 | |
| SCHEMBL4144907 | 0.70 | PNMT (0.46) | PNMTCES2HSD17B2OPRL1OPRM1 | |
| SCHEMBL7626469 | 0.70 | PNMT (0.62) | PNMTCES2ACP3GRIN2BIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101124200-A | Methods and fluorinated compositions for treating amyloid-related diseases | NEUROCHEM INTERNAT LTD (CH) | 2008-02-13 | — | — | CN | disclosed |