Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990350 | 0.84 | OPRM1 (0.38) | PNMTOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL4157268 | 0.83 | PNMT (0.58) | PNMTPDE2ACES2HSD17B2OPRM1 | |
| SCHEMBL8990452 | 0.79 | TSHR (0.43) | EPHX1 | |
| SCHEMBL29750658 | 0.77 | HTR2C (0.54) | PNMTPDE2ACES2HSD17B2OPRM1 | |
| SCHEMBL27698385 | 0.74 | PNMT (0.48) | PNMTPDE2ACES2HSD17B2OPRM1 | |
| SCHEMBL22816111 | 0.74 | HTR2C (0.57) | TACR1 | |
| SCHEMBL1498492 | 0.71 | LRRK2 (0.36) | PNMTTACR1 | |
| SCHEMBL8990301 | 0.71 | SLC6A2 (0.54) | SLC6A2SLC6A4 | |
| SCHEMBL27698323 | 0.71 | EPHX1 (0.46) | PNMTPDE2ACES2HSD17B2OPRM1 | |
| SCHEMBL11276420 | 0.71 | PNMT (0.50) | PNMTCES2HSD17B2OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536725-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1996-07-16 | — | — | US | disclosed |