Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GALK1 | P51570 | 1/20 | 0.39 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27698643 | 0.90 | LMNA (0.51) | LMNAALDH1A1SMN1; SMN2HTTPKM | |
| SCHEMBL27679669 | 0.81 | KMT2A (0.43) | LMNAALDH1A1SMN1; SMN2HTTMAPK1 | |
| SCHEMBL5262607 | 0.79 | ALDH1A1 (0.50) | LMNAALDH1A1SMN1; SMN2HTTPKM | |
| SCHEMBL27698653 | 0.76 | PTGS1 (0.42) | LMNAALDH1A1SMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL2186441 | 0.75 | L3MBTL1 (0.58) | LMNAALDH1A1PKMMAPK1L3MBTL1 | |
| SCHEMBL27698605 | 0.75 | PPARG (0.36) | MAPK1L3MBTL1RAB9ATSHR | |
| SCHEMBL27698608 | 0.74 | MEN1 (0.45) | LMNASMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL27679665 | 0.71 | LMNA (0.46) | LMNAALDH1A1SMN1; SMN2HTTMAPK1 | |
| SCHEMBL27679766 | 0.71 | LMNA (0.43) | LMNAALDH1A1SMN1; SMN2HTTNPC1 | |
| SCHEMBL27698640 | 0.69 | PPARG (0.32) | LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101031567-B | Novel heterocyclic NF-kB inhibitors | 4SC Corp.,Ltd. (DE) | 2011-12-21 | — | — | CN | disclosed |
| CN-101031567-A | Novel heterocyclic NF-kB inhibitors | 4SC AG (DE) | 2007-09-05 | — | — | CN | disclosed |