Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2186625 | 0.81 | MAPT (0.56) | L3MBTL1MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL2188543 | 0.80 | ALDH1A1 (0.52) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2186974 | 0.78 | CACNA2D1 (0.48) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL2188722 | 0.78 | KDM4E (0.57) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2188442 | 0.78 | NPC1 (0.47) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL27679675 | 0.78 | LMNA (0.50) | L3MBTL1MEN1KMT2AALDH1A1CNR1 | |
| SCHEMBL2187333 | 0.76 | MAPT (0.51) | L3MBTL1KMT2AALDH1A1LMNAALOX15 | |
| SCHEMBL27698643 | 0.76 | LMNA (0.51) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2189118 | 0.76 | F11 (0.48) | ALDH1A1CNR1LMNAALOX15TSHR | |
| SCHEMBL2187707 | 0.76 | MLNR (0.41) | L3MBTL1ALDH1A1LMNAALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343293-A1 | NOVEL PIPERIDIN-4-YL-THIAZOLE-CARBOXAMIDE ANALOGUES AS INHIBITORS OF T-CELL PROLIFERATION AND USES THEREOF | 4SC AG (DE) | 2011-07-13 | — | — | EP | disclosed |