Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21707063 | 0.73 | P2RY6 (0.33) | TGM2CES1 | |
| SCHEMBL21377402 | 0.73 | RAF1 (0.37) | TGM2CES1 | |
| SCHEMBL17385026 | 0.58 | P2RY6 (0.36) | — | |
| SCHEMBL8006749 | 0.56 | MMP12 (0.51) | — | |
| SCHEMBL18307135 | 0.55 | BRD4 (0.50) | TGM2CES1 | |
| SCHEMBL23652262 | 0.55 | TGM2 (0.47) | TGM2CES1 | |
| SCHEMBL24482971 | 0.53 | ESR1 (0.41) | TGM2CES1 | |
| SCHEMBL2227219 | 0.52 | MAOB (0.46) | — | |
| SCHEMBL7791509 | 0.52 | TGM2 (0.77) | TGM2CES1 | |
| SCHEMBL23201842 | 0.51 | ADRA2A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101605758-A | Methods of treating hepatitis C | PTC THERAPEUTICS INC (US) | 2009-12-16 | — | — | CN | disclosed |
| CN-101541748-A | Methods for treating hepatitis C | PTC THERAPEUTICS INC (US) | 2009-09-23 | — | — | CN | disclosed |
| CN-101027051-A | Methods for treating hepatitis C | PTC THERAPEUTICS INC (US) | 2007-08-29 | — | — | CN | disclosed |