Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 8/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | KLK1 | P06870 | 7/20 | 0.42 |
| ▸ | KLK6 | Q92876 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7877522 | 0.80 | LOXL2 (0.47) | PLGKLKB1PLAUPLATPRSS1 | |
| SCHEMBL7785365 | 0.79 | TPSAB1 (0.52) | PLGKLKB1PRSS1F10LOXL2 | |
| SCHEMBL327252 | 0.78 | LOXL2 (0.54) | PLGKLKB1PLAUPLATPRSS1 | |
| SCHEMBL12049311 | 0.77 | PLG (0.49) | PLGKLKB1PLAUPLATPRSS1 | |
| Hydrochloric Acid SCHEMBL7443406 | 0.76 | LOXL2 (0.52) | PLGKLKB1PLAUPLATPRSS1 | |
| Hydrochloric Acid SCHEMBL4888001 | 0.76 | PLG (0.50) | PLGKLKB1PLAULOXL2KLK1 | |
| SCHEMBL14949457 | 0.75 | MAPT (0.50) | KDM4EMEN1NPC1RAB9AKMT2A | |
| SCHEMBL28819098 | 0.74 | PLG (0.45) | PLGKLKB1PLAUPLATPRSS1 | |
| SCHEMBL319880 | 0.74 | KMT2A (0.47) | MEN1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL7670022 | 0.74 | ALDH1A1 (0.48) | KDM4EMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-87102765-A | The preparation method of sweeting agent N-guanidines guanidine-acetic acid and N-phenyl ethanamidine guanidine-acetic acid derivative and the prescription of this class sweeting agent | — | 1987-10-21 | — | — | CN | disclosed |