Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 7/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | USP7 | Q93009 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | DDT | P30046 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19721378 | 0.81 | KMT2A (0.47) | FYNMAP4K4USP7HTTKMT2A | |
| SCHEMBL2226848 | 0.80 | FYN (0.54) | FYNMAP4K4USP7HTTKMT2A | |
| SCHEMBL15359055 | 0.77 | USP7 (0.60) | FYNMAP4K4CHEK2MKNK1USP7 | |
| SCHEMBL12516853 | 0.77 | ADORA1 (0.49) | FYNMAP4K4USP7HTTKMT2A | |
| SCHEMBL29857982 | 0.77 | ADORA1 (0.49) | FYNMAP4K4USP7HTTKMT2A | |
| SCHEMBL26917180 | 0.77 | CHEK2 (0.53) | FYNMAP4K4CHEK2USP7HTT | |
| SCHEMBL29857829 | 0.77 | CHEK2 (0.53) | FYNMAP4K4CHEK2USP7HTT | |
| SCHEMBL27699381 | 0.77 | ALDH1A1 (0.46) | FYNMAP4K4CHEK2MKNK1USP7 | |
| SCHEMBL18770608 | 0.76 | MAP4K4 (0.47) | FYNMAP4K4DDT | |
| SCHEMBL12516834 | 0.76 | FYN (0.69) | FYNMAP4K4CHEK2MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101027302-B | Pyrrolo-pyridine kinase modulators | SGX PHARMACEUTICALS INC | 2011-05-11 | — | — | CN | disclosed |
| CN-101027302-A | Pyrrolo-pyridine kinase modulators | SGX PHARMACEUTICALS INC (US) | 2007-08-29 | — | — | CN | disclosed |