SCHEMBL27699588

SCHEMBL27699588

C(#CC1C2CC3CC(C2)CC1C3)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.42
SLC6A2 P23975 2/20 0.37
SLC6A4 P31645 2/20 0.37
SLC6A3 Q01959 2/20 0.37
FFAR1 O14842 1/20 0.35
MAPT P10636 3/20 0.34
KCNH2 Q12809 2/20 0.34
EPHX2 P34913 3/20 0.34
CYP3A4 P08684 3/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
CYP1A2 P05177 1/20 0.33
THPO P40225 1/20 0.33
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
GRM5 P41594 1/20 0.32
CHRNA1 P02708 1/20 0.32
CHRNG P07510 1/20 0.32
CHRNB1 P11230 1/20 0.32
CHRNB2 P17787 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2708869 0.72 HSD11B1 (0.33) KMT2A
SCHEMBL6683935 0.70 GRIN2D (0.33) APPKCNH2
SCHEMBL10457153 0.69 CYP2C9 (0.42) EPHX2CYP2C9
SCHEMBL18626138 0.67 APP (0.52) APPFFAR1MAPTKCNH2CYP3A4
SCHEMBL2565461 0.67 APP (0.52) APPFFAR1MAPTKCNH2CYP3A4
SCHEMBL3845906 0.66 APP (0.35) APPFFAR1KCNH2EPHX2GRM5
SCHEMBL2747858 0.64 APP (0.42) APPFFAR1MAPTKCNH2EPHX2
SCHEMBL11232546 0.64 FFAR1 (0.53) APPFFAR1MAPTKCNH2CYP1A2
SCHEMBL15266861 0.64 FFAR1 (0.49) APPFFAR1MAPTKCNH2CYP1A2
Diphenylacetylene SCHEMBL960609 0.64 APP (1.00) APPFFAR1MAPTKCNH2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101268119-B Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE CO 2011-08-17 CN disclosed
CN-101128514-B Benzoxazole resin precursor, polybenzoxazole resin, resin film and semiconductor device SUMITOMO BAKELITE CO 2011-05-25 CN disclosed
CN-101268119-A Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE CO (JP) 2008-09-17 CN disclosed
CN-101128514-A Benzoxazole resin precursor, polybenzoxazole resin, resin film and semiconductor device SUMITOMO BAKELITE CO (JP) 2008-02-20 CN disclosed