SCHEMBL27699593

SCHEMBL27699593

CCCc1cccc(C#CC23CC4CC(CC(C4)C2)C3)c1C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BID P55957 6/20 0.38
MCL1 Q07820 6/20 0.38
BCL2L1 Q07817 5/20 0.38
BAK1 Q16611 5/20 0.38
KAT8 Q9H7Z6 3/20 0.38
PPARA Q07869 3/20 0.38
PPARG P37231 2/20 0.38
EP300 Q09472 2/20 0.38
KAT5 Q92993 2/20 0.38
SAE1 Q9UBE0 2/20 0.38
KAT2A Q92830 1/20 0.38
KAT2B Q92831 1/20 0.38
F7 P08709 3/20 0.34
F3 P13726 3/20 0.34
MMP2 P08253 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
ALOX15 P16050 1/20 0.34
ECE1 P42892 1/20 0.34
SGMS1 Q86VZ5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2708211 0.80 KDM4E (0.41) KDM4EMAPTHSD17B10MEN1KMT2A
SCHEMBL27518648 0.72 BID (0.48) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL5162912 0.71 BID (0.59) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL5164770 0.65 BID (0.53) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL1355661 0.65 BID (0.53) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL2129140 0.65 BID (0.76) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL31319546 0.65 BID (0.53) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL2709686 0.64 STS (0.40) KDM4EMAPTALOX15HSD17B10MEN1
SCHEMBL2706953 0.64 STS (0.40) KDM4EMAPTALOX15HSD17B10MEN1
SCHEMBL5163919 0.64 BID (0.51) BIDMCL1BCL2L1BAK1KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101268119-B Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE CO 2011-08-17 CN disclosed
CN-101128514-B Benzoxazole resin precursor, polybenzoxazole resin, resin film and semiconductor device SUMITOMO BAKELITE CO 2011-05-25 CN disclosed
CN-101268119-A Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE CO (JP) 2008-09-17 CN disclosed
CN-101128514-A Benzoxazole resin precursor, polybenzoxazole resin, resin film and semiconductor device SUMITOMO BAKELITE CO (JP) 2008-02-20 CN disclosed