Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27508637 | 0.82 | MAPT (0.44) | KDM4EALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL5218939 | 0.78 | PIK3CB (0.53) | L3MBTL1KDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL5453917 | 0.77 | PIK3CB (0.58) | L3MBTL1KDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL14818929 | 0.75 | KMT2A (0.64) | L3MBTL1KDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL14804579 | 0.74 | CYP1A2 (0.60) | L3MBTL1KDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL14804472 | 0.71 | IGF1R (0.45) | L3MBTL1KDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL10102116 | 0.70 | CRHBP (0.46) | L3MBTL1KDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL28796489 | 0.69 | MEN1 (0.56) | KMT2AMEN1PIK3CBAKT1 | |
| SCHEMBL28796567 | 0.69 | AKT1 (0.55) | PIK3CBAKT1 | |
| SCHEMBL27863831 | 0.69 | MEN1 (0.56) | KMT2AMEN1PIK3CBAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101023063-A | Azine-carboxamides as anti-cancer agents | ASTRAZENECA AB (SE) | 2007-08-22 | — | — | CN | disclosed |