Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.54 |
| ▸ | CTSL | P07711 | 7/20 | 0.54 |
| ▸ | CTSS | P25774 | 7/20 | 0.54 |
| ▸ | CTSB | P07858 | 6/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12327746 | 0.86 | ALDH1A1 (0.56) | CTSKCTSLCTSSCTSBCTRB1 | |
| SCHEMBL16215404 | 0.84 | CTRB1 (0.52) | CTSKCTSLCTSSCTSBCTRB1 | |
| Trimethylammonium SCHEMBL28037498 | 0.80 | ELANE (0.52) | CTSKCTSLCTSSCTSBCTRB1 | |
| SCHEMBL241564 | 0.80 | CTSK (0.61) | CTSKCTSLCTSSCTSBCTRB1 | |
| SCHEMBL856196 | 0.80 | CTSK (0.61) | CTSKCTSLCTSSCTSBCTRB1 | |
| SCHEMBL241565 | 0.80 | CTSK (0.61) | CTSKCTSLCTSSCTSBCTRB1 | |
| SCHEMBL6979650 | 0.79 | CTRB1 (0.65) | CTSKCTSLCTSSCTSBCTRB1 | |
| SCHEMBL7886288 | 0.79 | CTRB1 (0.60) | CTSKCTSLCTSSCTSBCTRB1 | |
| SCHEMBL20529450 | 0.79 | CTRB1 (0.60) | CTSKCTSLCTSSCTSBCTRB1 | |
| SCHEMBL29467644 | 0.79 | CTRB1 (0.60) | CTSKCTSLCTSSCTSBCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101175725-B | Process for the preparation of opioid modulators | JANSSEN PHARMACEUTICA NV | 2011-02-02 | — | — | CN | disclosed |
| CN-101175725-A | Process for the preparation of opioid modulators | JANSSEN PHARMACEUTICA NV (BE) | 2008-05-07 | — | — | CN | disclosed |
| CN-101175726-A | Process for the preparation of opioid modulators | JANSSEN PHARMACEUTICA NV (BE) | 2008-05-07 | — | — | CN | disclosed |