Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27906422 | 0.84 | — | — | |
| SCHEMBL4194567 | 0.84 | IDO1 (0.33) | CNR2TP53GPR119 | |
| SCHEMBL28031589 | 0.84 | — | — | |
| SCHEMBL28016518 | 0.79 | EPHX2 (0.36) | TP53GPR119 | |
| SCHEMBL27514159 | 0.79 | GPR119 (0.32) | TP53GPR119 | |
| SCHEMBL18166970 | 0.77 | CHRM2 (0.38) | ALDH1A1GPR119 | |
| SCHEMBL16349436 | 0.77 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL27751949 | 0.77 | HPGD (0.34) | — | |
| SCHEMBL27623657 | 0.76 | POLB (0.40) | TP53ALDH1A1ATM | |
| SCHEMBL27657045 | 0.76 | RIPK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110950839-B | Preparation method of 4- (4-halo-1H-pyrazol-1-yl) piperidine-1-carboxylic acid tert-butyl ester | 蚌埠中实化学技术有限公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-110950839-A | Preparation method of 4- (4-halo-1H-pyrazol-1-yl) piperidine-1-carboxylic acid tert-butyl ester | 蚌埠中实化学技术有限公司 | 2020-04-03 | — | — | CN | disclosed |
| CN-101479274-B | Pharmaceutical compounds | HOFFMANN LA ROCHE | 2013-06-12 | — | — | CN | disclosed |
| CN-101087794-B | Pharmaceutical compounds | HOFFMANN LA ROCHE | 2011-05-18 | — | — | CN | disclosed |
| CN-101087794-A | Pharmaceutical compounds | PIRAMED LTD (GB) | 2007-12-12 | — | — | CN | disclosed |