Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.37 |
| ▸ | MMP3 | P08254 | 3/20 | 0.37 |
| ▸ | MMP7 | P09237 | 3/20 | 0.37 |
| ▸ | MMP13 | P45452 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10181326 | 1.00 | MMP1 (0.37) | MMP1MMP3MMP7MMP13NPSR1 | |
| SCHEMBL8532100 | 0.81 | MAPT (0.37) | GAACYP2C19FKBP1A | |
| SCHEMBL19369809 | 0.79 | FDPS (0.32) | MMP1MMP3MMP7MMP13 | |
| SCHEMBL25711383 | 0.79 | ACE (0.37) | MMP1MMP3MMP7MMP13HSD17B10 | |
| SCHEMBL7219514 | 0.76 | MMP1 (0.45) | MMP1MMP3MMP7MMP13NPSR1 | |
| SCHEMBL2772253 | 0.74 | — | — | |
| SCHEMBL15482785 | 0.73 | NPSR1 (0.36) | MMP1MMP3MMP7MMP13NPSR1 | |
| SCHEMBL337199 | 0.73 | NR1H2 (0.42) | NPSR1HSD17B10FKBP1A | |
| SCHEMBL18745636 | 0.73 | NR1H2 (0.42) | NPSR1HSD17B10FKBP1A | |
| SCHEMBL22019554 | 0.72 | FKBP1A (0.48) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101035776-A | Enantiomerically pure heterocyclic compounds for the preparation of peptides potentially useful as medicaments | SOLVAY (BE) | 2007-09-12 | — | — | CN | disclosed |