Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.31 |
| ▸ | AKT1 | P31749 | 2/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL908028 | 0.82 | HRH4 (0.36) | HRH4TRPV1SLC9A1PTPN11MAPT | |
| SCHEMBL28768832 | 0.82 | MPL (0.42) | — | |
| SCHEMBL27701427 | 0.81 | GRM2 (0.35) | TRPV1SLC9A1RPS6KB1AKT1GRM2 | |
| SCHEMBL27701429 | 0.79 | MGLL (0.36) | PTPN11UCHL1USP30GRM2 | |
| SCHEMBL27701415 | 0.77 | SCN9A (0.34) | MAPTMEN1KMT2A | |
| SCHEMBL27701428 | 0.76 | CHRM1 (0.34) | MAPT | |
| SCHEMBL907694 | 0.75 | CASP1 (0.40) | HRH4TRPV1PTPN11MEN1KMT2A | |
| SCHEMBL27701424 | 0.74 | CXCR3 (0.38) | TRPV1 | |
| SCHEMBL27701416 | 0.74 | KMT2A (0.37) | HRH4MAPTKMT2A | |
| SCHEMBL27682277 | 0.74 | TRPV1 (0.35) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101014587-A | Substituted biaryl piperazinyl-pyridine analogues | NEUROGEN CORP (US) | 2007-08-08 | — | — | CN | claimed |