Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.62 |
| ▸ | RAB9A | P51151 | 8/20 | 0.62 |
| ▸ | NPC1 | O15118 | 6/20 | 0.62 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.54 |
| ▸ | MEN1 | O00255 | 8/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3649157 | 0.85 | GAA (0.54) | MAPTRAB9ANPC1GLO1GAA | |
| SCHEMBL27682757 | 0.82 | GLO1 (0.61) | MAPTGLO1GAAKMT2AMEN1 | |
| SCHEMBL1231354 | 0.81 | MAPT (0.70) | MAPTRAB9ANPC1GAAKMT2A | |
| SCHEMBL1231353 | 0.81 | MAPT (0.70) | MAPTRAB9ANPC1GAAKMT2A | |
| SCHEMBL2996974 | 0.80 | HSP90AA1 (0.57) | MAPTRAB9ANPC1GLO1GAA | |
| SCHEMBL2996979 | 0.80 | HSP90AA1 (0.57) | MAPTRAB9ANPC1GLO1GAA | |
| SCHEMBL1165592 | 0.79 | MAPT (0.68) | MAPTRAB9ANPC1GAAKMT2A | |
| SCHEMBL1165591 | 0.79 | MAPT (0.68) | MAPTRAB9ANPC1GAAKMT2A | |
| SCHEMBL28684828 | 0.76 | MAPT (0.61) | MAPTRAB9ANPC1GAAKMT2A | |
| SCHEMBL10038665 | 0.75 | MAPT (0.65) | MAPTRAB9ANPC1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100506808-C | 4-(2-Benzothiazolyl aminoiminomethyl) phenoxyacetic acid and cupric complexes and preparation methods thereof | UNIV SICHUAN (CN) | 2009-07-01 | — | — | CN | disclosed |
| CN-101037421-A | 4-(2-Benzothiazolyl aminoiminomethyl) phenoxyacetic acid and cupric complexes and preparation methods thereof | UNIV SICHUAN (CN) | 2007-09-19 | — | — | CN | disclosed |