SCHEMBL27701997

SCHEMBL27701997

c1ccc(CCN2CCOC2)cc1

nearest known ligand 0.64

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.64
POLB P06746 1/20 0.64
SLC6A3 Q01959 1/20 0.58
HTR1A P08908 1/20 0.51
DRD2 P14416 1/20 0.51
MAOA P21397 1/20 0.50
ACHE P22303 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
CCR3 P51677 1/20 0.49
ALDH1A1 P00352 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9539677 0.89 SIGMAR1 (0.79) SIGMAR1POLBSLC6A3HTR1ADRD2
SCHEMBL78043 0.89 SIGMAR1 (0.79) SIGMAR1POLBSLC6A3HTR1ADRD2
Ethylene SCHEMBL28207535 0.85 SIGMAR1 (0.74) SIGMAR1POLBSLC6A3HTR1ADRD2
Methylamine SCHEMBL28040222 0.84 SIGMAR1 (0.72) SIGMAR1POLBSLC6A3HTR1ADRD2
SCHEMBL9876165 0.81 SIGMAR1 (0.59) SIGMAR1POLBMEN1KMT2AALDH1A1
Isothiocyanate SCHEMBL2892892 0.80 SIGMAR1 (0.66) SIGMAR1POLBSLC6A3HTR1ADRD2
SCHEMBL21465700 0.79 SIGMAR1 (0.65) SIGMAR1POLBSLC6A3HTR1ADRD2
Sulfurous Acid SCHEMBL27938413 0.78 SIGMAR1 (0.64) SIGMAR1POLBSLC6A3HTR1ADRD2
SCHEMBL1711070 0.78 SIGMAR1 (1.00) SIGMAR1POLBKMT2ACCR3
SCHEMBL13150782 0.78 SLC6A3 (0.83) SIGMAR1SLC6A3HTR1ADRD2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101045713-A Synthesis method of phenethyl oxazolidine 2,4-diketone NINGBO INST TECH ZHEJIANG UNIV (CN) 2007-10-03 CN disclosed