SCHEMBL9876165

SCHEMBL9876165

c1ccc(CN2CCOC2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.59
HRH3 Q9Y5N1 2/20 0.55
POLB P06746 1/20 0.53
ALDH1A1 P00352 3/20 0.53
HTT P42858 2/20 0.53
KDM4E B2RXH2 1/20 0.53
HPGD P15428 1/20 0.53
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
TSHR P16473 1/20 0.50
MC4R P32245 1/20 0.50
NCF1 P14598 1/20 0.50
ADRA2A P08913 1/20 0.49
ADRA2B P18089 1/20 0.49
ADRA2C P18825 1/20 0.49
TMEM97 Q5BJF2 1/20 0.49
DRD4 P21917 2/20 0.49
CYP2A13 Q16696 1/20 0.49
MEN1 O00255 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10199478 0.89 SIGMAR1 (0.55) SIGMAR1HRH3POLBALDH1A1MC4R
SCHEMBL102338 0.88 SIGMAR1 (0.71) SIGMAR1HRH3POLBALDH1A1HTT
SCHEMBL6200777 0.88 SIGMAR1 (0.71) SIGMAR1HRH3POLBALDH1A1HTT
SCHEMBL2678678 0.88 SIGMAR1 (0.58) SIGMAR1POLBALDH1A1TSHRMC4R
SCHEMBL896379 0.86 SIGMAR1 (0.68) SIGMAR1HRH3POLBALDH1A1HTT
Hydrochloric Acid SCHEMBL6261135 0.86 SIGMAR1 (0.68) SIGMAR1HRH3POLBALDH1A1HTT
Water SCHEMBL1702298 0.86 SIGMAR1 (0.68) SIGMAR1HRH3POLBALDH1A1HTT
SCHEMBL948372 0.86 SIGMAR1 (0.68) SIGMAR1HRH3POLBALDH1A1HTT
SCHEMBL18065638 0.86 SIGMAR1 (0.68) SIGMAR1HRH3POLBALDH1A1HTT
SCHEMBL28158277 0.86 SIGMAR1 (0.68) SIGMAR1HRH3POLBALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0011598-B1 PROCESS FOR THE PREPARATION OF DERIVATIVES OF ISOEUGENOL DIMERS PLC PHARMACEUTICAL LICENCES COMPANY LTD. (CH) 1983-01-26 EP claimed
EP-0011598-A1 Process for the preparation of derivatives of isoeugenol dimers PLC PHARMACEUTICAL LICENCES COMPANY LTD. (CH) 1980-05-28 EP claimed
CN-118666740-A Synthesis of surface chiral [2.2] cyclopyridine/lactam compound by parallel kinetic resolution and preparation method thereof 贵州大学 2024-09-20 CN disclosed
US-11622916-B2 Photocurable composition excellent in curing depth SHOFU INC. (JP) 2023-04-11 US disclosed
CN-115068347-A Photocurable composition having excellent depth of cure 株式会社松风 2022-09-20 CN disclosed
US-20220287919-A1 PHOTOCURABLE COMPOSITION EXCELLENT IN CURING DEPTH SHOFU INC. (JP) 2022-09-15 US disclosed
EP-4056164-A1 PHOTOCURABLE COMPOSITION EXCELLENT IN CURING DEPTH Shofu Inc. (JP) 2022-09-14 EP disclosed
US-11155511-B2 Distillation process for production of acrylic acid NOVOMER, INC. (US) 2021-10-26 US disclosed
US-20200347004-A1 DISTILLATION PROCESS FOR PRODUCTION OF ACRYLIC ACID NOVOMER, INC. 2020-11-05 US disclosed
US-10717695-B2 Distillation process for production of acrylic acid NOVOMER, INC. (US) 2020-07-21 US disclosed
US-10703702-B2 Production system/production process for acrylic acid and precursors thereof NOVOMER, INC. (US) 2020-07-07 US disclosed
US-20150093694-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-04-02 US disclosed
US-20150093693-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-04-02 US disclosed
US-5013668-A Reservoirs, conduits allowing diffusional migration of component, reagent, surface tension IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-05-07 US disclosed
EP-0011598-B1 PROCESS FOR THE PREPARATION OF DERIVATIVES OF ISOEUGENOL DIMERS PLC PHARMACEUTICAL LICENCES COMPANY LTD. (CH) 1983-01-26 EP disclosed
US-4256764-A LIVER DISORDERS; WATER SOLUBILITY; REACTION WITH AN OXAZOLIDINE PLC PHARMACEUTICAL LICENSES CO. LTD. (CH) 1981-03-17 US disclosed
EP-0011598-A1 Process for the preparation of derivatives of isoeugenol dimers PLC PHARMACEUTICAL LICENCES COMPANY LTD. (CH) 1980-05-28 EP disclosed
US-4089865-A Certain thiazole compounds SYNTEX (U.S.A.) INC. (US) 1978-05-16 US disclosed
US-4001421-A THIAZOLE CARDIOVASCULAR AGENTS SYNTEX (U.S.A.) INC. (US) 1977-01-04 US disclosed
US-3982010-A Thiazole cardiovascular agents SYNTEX (U.S.A.) INC. (US) 1976-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10703702-B2 Production system/production process for acrylic acid and precursors thereof PCCA, COASY, ALAD SIGMAR1 4207/4885HRH3 3406/4885POLB 1206/4885
US-11155511-B2 Distillation process for production of acrylic acid ALAD, PCCA, ADSL SIGMAR1 4797/4885HRH3 1923/4885POLB 768/4885
US-20200347004-A1 DISTILLATION PROCESS FOR PRODUCTION OF ACRYLIC ACID ALAD, PCCA, ADSL SIGMAR1 4797/4885HRH3 1923/4885POLB 768/4885
US-10717695-B2 Distillation process for production of acrylic acid ALAD, PCCA, ADSL SIGMAR1 4797/4885HRH3 1923/4885POLB 768/4885
US-11622916-B2 Photocurable composition excellent in curing depth ODC1, AOC2, CCNT1 SIGMAR1 820/4885HRH3 253/4885POLB 226/4885
US-20220287919-A1 PHOTOCURABLE COMPOSITION EXCELLENT IN CURING DEPTH ODC1, AOC2, CCNT1 SIGMAR1 810/4885HRH3 258/4885POLB 224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.