Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TYMP | P19971 | 4/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8827975 | 0.83 | TK1 (0.52) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL8745678 | 0.83 | TK1 (0.52) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL13208038 | 0.83 | TK1 (0.51) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL2987732 | 0.83 | TK1 (0.51) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL14115636 | 0.79 | TK1 (0.48) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL8004092 | 0.74 | TK1 (0.48) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL8541527 | 0.74 | TK1 (0.63) | TK1DHFR | |
| SCHEMBL6909337 | 0.73 | LMNA (0.72) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL16774560 | 0.73 | LMNA (0.72) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL16774561 | 0.73 | LMNA (0.72) | TK1ALDH1A1LMNAALBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161439-B1 | XYLO-LNA ANALOGUES | EXIQON AS (DK) | 2010-04-21 | — | — | EP | disclosed |
| US-7084125-B2 | Xylo-LNA analogues | EXIQON A/S (DK) | 2006-08-01 | — | — | US | disclosed |