Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.52 |
| ▸ | DHFR | P00374 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TYMP | P19971 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8827975 | 1.00 | TK1 (0.52) | TK1DHFRLMNAALDH1A1ALB | |
| SCHEMBL9218555 | 0.86 | ALDH1A1 (0.49) | TK1DHFRLMNAALDH1A1ALB | |
| SCHEMBL5982146 | 0.86 | ALDH1A1 (0.49) | TK1DHFRLMNAALDH1A1ALB | |
| SCHEMBL25701920 | 0.84 | TK1 (0.55) | TK1DHFRLMNAALDH1A1ALB | |
| SCHEMBL2770232 | 0.83 | TK1 (0.49) | TK1DHFRLMNAALDH1A1ALB | |
| SCHEMBL17826624 | 0.83 | DHFR (0.53) | TK1DHFRLMNAALDH1A1ALB | |
| SCHEMBL14429108 | 0.83 | ALDH1A1 (0.47) | TK1DHFRLMNAALDH1A1ALB | |
| SCHEMBL14568793 | 0.83 | ALDH1A1 (0.47) | TK1DHFRLMNAALDH1A1ALB | |
| SCHEMBL17826619 | 0.82 | DHFR (0.49) | TK1DHFRLMNAALDH1A1ALB | |
| SCHEMBL14115636 | 0.82 | TK1 (0.48) | TK1DHFRLMNAALDH1A1ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653435-B1 | Process for large scale preparation of 2',3'-didehydro-2',3'-dideonucleosides | BRISTOL MYERS SQUIBB CO (US) | 1997-02-05 | — | — | EP | claimed |
| EP-0464642-A1 | Pyrimidine derivatives, their preparation and use as well as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-08 | — | — | EP | disclosed |