Mannitol

Mannitol

SCHEMBL27702736

CC(O)C(C)(O)O.OCC(CO)(CO)CO.OCC(CO)(CO)COCC(CO)(CO)CO.OCC(O)C(O)C(O)C(O)CO

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
KDM4E B2RXH2 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mannitol SCHEMBL28694175 0.85 LMNA (0.52) LMNAL3MBTL1TDP1KDM4E
Mannitol SCHEMBL4205639 0.85 LMNA (0.52) LMNAL3MBTL1TDP1KDM4E
E968 SCHEMBL20515145 0.77 LMNA (0.36) LMNAL3MBTL1TDP1
SCHEMBL28222497 0.77 ALDH1A1 (0.37) LMNATDP1
Propylene Glycol SCHEMBL28636759 0.75 TDP1 (0.50) TDP1
Sorbitol SCHEMBL2087831 0.74 LMNA (0.69) LMNAL3MBTL1TDP1KDM4E
Mannitol SCHEMBL29111380 0.74 LMNA (0.69) LMNAL3MBTL1TDP1KDM4E
Mannitol SCHEMBL8952346 0.74 LMNA (0.69) LMNAL3MBTL1TDP1KDM4E
Mannitol SCHEMBL1608397 0.74 LMNA (0.69) LMNAL3MBTL1TDP1KDM4E
Sorbitol SCHEMBL5144596 0.73 PDE4A (0.39) LMNAL3MBTL1TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101085851-A Preparation method for PVC cable material HANGZHOU XINXIN PLASTICS AUX Y (CN) 2007-12-12 CN disclosed