Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4435855 | 0.92 | CNR2 (0.52) | TNFLMNAHPGDGAAL3MBTL1 | |
| SCHEMBL4441848 | 0.88 | CACNA1A (0.57) | TNFLMNAHPGDGAAKMT2A | |
| SCHEMBL11071292 | 0.85 | L3MBTL1 (0.61) | TNFL3MBTL1FFAR1CYP1A2CYP2D6 | |
| SCHEMBL6484578 | 0.85 | FFAR1 (0.66) | LMNAHPGDGAAL3MBTL1KMT2A | |
| SCHEMBL628797 | 0.85 | LMNA (0.56) | LMNAHPGDGAAL3MBTL1KMT2A | |
| SCHEMBL12883281 | 0.84 | TNF (0.54) | TNFGAAL3MBTL1KMT2AFFAR1 | |
| SCHEMBL3443782 | 0.84 | L3MBTL1 (0.67) | TNFL3MBTL1FFAR1CYP1A2CYP2D6 | |
| SCHEMBL6289377 | 0.82 | TNF (0.52) | TNFL3MBTL1KMT2AFFAR1CYP1A2 | |
| SCHEMBL4459742 | 0.82 | TNF (0.52) | TNFLMNAGAAL3MBTL1KMT2A | |
| SCHEMBL6226631 | 0.81 | TNF (0.49) | TNFLMNAL3MBTL1FFAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101053558-A | Diphenylethylene compounds and uses thereof | CELGENE CORP (US) | 2007-10-17 | — | — | CN | disclosed |