Pyrophosphoric Acid

Pyrophosphoric Acid

SCHEMBL2770398

O=P(O)(O)OP(=O)(O)O.[Pt]

nearest known ligand 0.91

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ FDPS P14324 1/20 0.91
▸ BLM P54132 1/20 0.91
▸ TDP1 Q9NUW8 1/20 0.91
▸ CA4 P22748 1/20 0.37
▸ CA2 P00918 1/20 0.36
▸ INPPL1 O15357 2/20 0.35
▸ INPP5A Q14642 2/20 0.35
▸ SMPD1 P17405 1/20 0.35
▸ INPP5B P32019 1/20 0.35
▸ BTN3A1 O00481 2/20 0.35
▸ ITPR3 Q14573 3/20 0.33
▸ SLC34A1 Q06495 1/20 0.33
▸ ITPR2 Q14571 1/20 0.33
▸ ITPR1 Q14643 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrophosphoric Acid SCHEMBL21647245 0.96 FDPS (0.83) FDPSBLMTDP1CA4CA2
Pyrophosphoric Acid SCHEMBL292348 0.95 FDPS (1.00) FDPSBLMTDP1CA4CA2
Pyrophosphoric Acid SCHEMBL29634664 0.95 — —
Pyrophosphoric Acid SCHEMBL3654 0.95 — —
Pyrophosphoric Acid SCHEMBL8851914 0.95 FDPS (1.00) FDPSBLMTDP1CA4CA2
Pyrophosphoric Acid SCHEMBL23537580 0.91 FDPS (0.91) FDPSBLMTDP1CA4CA2
Pyrophosphoric Acid SCHEMBL21145230 0.91 FDPS (0.91) FDPSBLMTDP1CA4CA2
Pyrophosphoric Acid SCHEMBL396637 0.91 FDPS (0.91) FDPSBLMTDP1CA4CA2
Pyrophosphoric Acid SCHEMBL21433694 0.91 FDPS (0.91) FDPSBLMTDP1CA4CA2
Pyrophosphoric Acid SCHEMBL11587546 0.91 FDPS (0.91) FDPSBLMTDP1CA4CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3565561-B1 PHOSPHAPLATIN COMPOUNDS AS THERAPEUTIC AGENTS FOR TREATMENT OF BONE BLOOD CANCERS PROMONTORY THERAPEUTICS INC (US) 2026-05-06 — — EP claimed
US-11439619-B2 Phosphaplatin compounds as immuno-modulatory agents and therapeutic uses thereof PHOSPLATIN THERAPEUTICS INC. (US) 2022-09-13 — — US claimed
US-20210121434-A1 Phosphaplatin Compounds as Immuno-Modulatory Agents and Therapeutic Uses Thereof PHOSPLATIN THERAPEUTICS LLC (US) 2021-04-29 — — US claimed
EP-3679046-A1 PHOSPHAPLATIN COMPOUNDS AS IMMUNO-MODULATORY AGENTS AND THERAPEUTIC USES THEREOF Phosplatin Therapeutics LLC (US) 2020-07-15 — — EP claimed
CN-111328330-A Phosphaplatins as immunomodulators and their therapeutic use 弗斯普拉廷治疗有限责任公司 2020-06-23 — — CN claimed
US-10668080-B2 Phosphaplatin compounds as therapeutic agents for treatment of bone or blood cancers PHOSPLATIN THERAPEUTICS LLC (US) 2020-06-02 — — US claimed
CN-106967124-B Synthesis and purification method of phosphorus platinum compound and application thereof 弗斯普拉廷治疗有限责任公司 2020-03-06 — — CN claimed
EP-3565561-A1 PHOSPHAPLATIN COMPOUNDS AS THERAPEUTIC AGENTS FOR TREATMENT OF BONE BLOOD CANCERS Phosplatin Therapeutics LLC (US) 2019-11-13 — — EP claimed
US-20190328748-A1 PHOSPHAPLATIN COMPOUNDS AS THERAPEUTIC AGENTS FOR TREATMENT OF BONE OR BLOOD CANCERS PROMONTORY THERAPEUTICS INC. 2019-10-31 — — US claimed
EP-3202769-B1 PURIFICATION METHOD FOR PHOSPHAPLATIN COMPOUNDS PHOSPLATIN THERAPEUTICS LLC (US) 2019-10-02 — — EP claimed
CN-104540839-B Synthesis and purification method of phosphorus platinum compound and application thereof 弗斯普拉廷治疗有限责任公司 2017-02-22 — — CN claimed
EP-2855496-B1 SYNTHETIC AND PURIFICATION METHODS FOR PHOSPHAPLATIN COMPOUNDS AND USES THEREOF PHOSPLATIN THERAPEUTICS LLC (US) 2016-12-14 — — EP claimed
CN-104540839-A Synthesis and purification method of phosphorus platinum compound and application thereof PHOSPLATIN THERAPEUTICS LLC 2015-04-22 — — CN claimed
EP-2855496-A1 SYNTHETIC AND PURIFICATION METHODS FOR PHOSPHAPLATIN COMPOUNDS AND USES THEREOF Phosplatin Therapeutics LLC (US) 2015-04-08 — — EP claimed
US-8859796-B1 Synthetic and purification methods for phosphaplatin compounds and uses thereof Phosplatin Therapeutics (US) 2014-10-14 — — US claimed
US-8846964-B2 Synthetic method for phosphaplatin compounds Phosplatin Therapeutics (US) 2014-09-30 — — US claimed
US-20140288321-A1 Synthetic and Purification Methods for Phosphaplatin Compounds and Uses Thereof PHOSPLATIN THERAPEUTICS LLC (US) 2014-09-25 — — US claimed
US-20140024848-A1 Synthetic Method for Phosphaplatin Compounds PHOSPLATIN THERAPEUTICS LLC (US) 2014-01-23 — — US claimed
WO-2013176764-A1 SYNTHETIC AND PURIFICATION METHODS FOR PHOSPHAPLATIN COMPOUNDS AND USES THEREOF PHOSPLATIN THERAPEUTICS LLC (US) 2013-11-28 — — WO claimed
US-4052323-A HIGH-TEMPERATURE LUBRICANT FOR THE HOT-WORKING OF METALS LONZA, LTD. (CH) 1977-10-04 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140288321-A1 Synthetic and Purification Methods for Phosphaplatin Compounds and Uses Thereof PHOSPHO1, PPIP5K2, PEBP1 FDPS 427/4885BLM 2464/4885TDP1 3160/4885
US-20190328748-A1 PHOSPHAPLATIN COMPOUNDS AS THERAPEUTIC AGENTS FOR TREATMENT OF BONE OR BLOOD CANCERS PHOSPHO1, PHPT1, PPIP5K2 FDPS 2400/4885BLM 1979/4885TDP1 2510/4885
US-20140024848-A1 Synthetic Method for Phosphaplatin Compounds PPIP5K2, PHOSPHO1, PEBP1 FDPS 180/4885BLM 2467/4885TDP1 3217/4885
US-11439619-B2 Phosphaplatin compounds as immuno-modulatory agents and therapeutic uses thereof PDCD1, PDCD4, PDCD1LG2 FDPS 1436/4885BLM 2089/4885TDP1 2661/4885
US-20210121434-A1 Phosphaplatin Compounds as Immuno-Modulatory Agents and Therapeutic Uses Thereof PDCD1, PDCD4, PDCD1LG2 FDPS 1436/4885BLM 2089/4885TDP1 2661/4885
US-10668080-B2 Phosphaplatin compounds as therapeutic agents for treatment of bone or blood cancers PHOSPHO1, MPL, PPIP5K2 FDPS 2576/4885BLM 1761/4885TDP1 2575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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