Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27704149 | 0.82 | HRH4 (0.36) | PTGES2ALPLSLC22A12SLC40A1KIF11 | |
| SCHEMBL27690268 | 0.78 | NFE2L2 (0.50) | ALPLGAABCHEACHEALDH1A1 | |
| SCHEMBL14686367 | 0.76 | L3MBTL1 (0.46) | PTGES2GAASLC22A12ALDH1A1L3MBTL1 | |
| SCHEMBL27418721 | 0.76 | ALDH1A1 (0.47) | PTGES2ALPLGAASLC22A12ALDH1A1 | |
| SCHEMBL1046653 | 0.76 | PTGES2 (0.40) | PTGES2GAAALDH1A1L3MBTL1ANO1 | |
| SCHEMBL96815 | 0.76 | ALDH1A1 (0.55) | PTGES2GAAALDH1A1CCR3RXRA | |
| SCHEMBL13012160 | 0.74 | PTGES2 (0.53) | PTGES2BCHEACHEANO1 | |
| SCHEMBL13012177 | 0.73 | PTGES2 (0.55) | PTGES2GAABCHEACHESLC22A12 | |
| Formaldehyde SCHEMBL27526817 | 0.73 | ALDH1A1 (0.52) | PTGES2GAAALDH1A1CCR3RXRA | |
| SCHEMBL2646108 | 0.73 | ALPL (0.46) | PTGES2ALPLSLC22A12SLC40A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101180266-A | Alpha ketoamide compounds as cysteine protease inhibitors | APPLERA CORP (US) | 2008-05-14 | — | — | CN | disclosed |